NEANDERTHAL_ALTAI_F_all-L9105_CombinedKit.txtis 3.832% Likely to be Male
NEANDERTHAL_ALTAI_F_all-L9105_CombinedKit.txtis 96.168% Likely to be Female
0 A variants out of 0 Total
0 B variants out of 0 Total
0 C variants out of 2 Total
0 D variants out of 0 Total
0 E variants out of 1 Total
0 E1b variants out of 0 Total
0 E3b variants out of 0 Total
0 F variants out of 0 Total
0 G variants out of 2 Total
0 H variants out of 0 Total
0 IJ variants out of 2 Total
0 I variants out of 3 Total
0 I1 variants out of 0 Total
0 I2 variants out of 0 Total
0 J variants out of 0 Total
0 J1 variants out of 0 Total
0 J1a variants out of 0 Total
0 J1b variants out of 0 Total
0 J2 variants out of 0 Total
0 J2a variants out of 0 Total
0 J2b variants out of 0 Total
0 K variants out of 0Total
0 L variants out of 2Total
0 N variants out of 0Total
0 O variants out of 2Total
0 Q variants out of 0Total
0 Q1 variants out of 0Total
0 Q2 variants out of 0Total
0 R variants out of 4Total
0 R1a variants out of 0Total
0 R1b variants out of 0Total
0 R2 variants out of 0Total
Results Mental Health
GG in COMT's Val/Met variation, meaning Val/Val , or warrior , higher activity of the COMT enzyme and quicker breakdown of dopamine. Individuals with this have advantages in stress resilience but disadvantages in attention tasks.
GG in COMT's rs6267, which is the typical for most humans and leads to slightly lower risk of Schizophrenia
GG in COMT's rs165599 variation, which typically results in higher risk of Schizophrenia and Bipolar disorder.
TT in MAOA's rs6323, leading to lower activity of the MAOA enzyme and slower breakdown of dopamine, thus higher dopamine levels and certain advantages in attention tasks.
GG, which means no derived No-Go Learner variants in DRD2's Pro319Pro variation, which means a higher number of D2 receptor sites in the brain, and a higher likelihood of schizophrenia
AA in DRD2's rs6275 variation, meaning increased number of dopamine D2 receptors and a higher risk of Schizophrenia.
AA in rs4648317 of DRD2, which is implicated in an increased number of Dopamine D2 receptor sites in the brain and an increased likelihood of Schizophrenia.
AA in Taq1 variation of DRD2, which is implicated in a greatly decreased number of Dopamine D2 receptor sites in the brain and an increased likelihood of Alcoholism, Parkinson's, ADHD, and various other illnesses. This is not a typical human .
CC in rs1076560 of DRD2, which is the typical for most humans leading to a slightly higher number of D2 dopamine receptors and better memory performance.
CC in rs5326 of DRD1, which is the typical for most humans and leads to a slightly lower risk of various mental health conditions.
AA in rs686 of Dopamine Receptor D1 gene, which leads to a higher likelyhood of Autism.
TT in rs4532 of DRD1, a typical associated with slightly higher odds of Autism and tobacco addiction.
GG in rs265981 of DRD1, which is the typical for most humans, and leads to a slightly higher risk of Schizophrenia and nicotine dependence.
CC in rs6280 of DRD3, a rare which is implicated in higher odds of OCD and intellectual disability.
GG in DRD3's rs167771 variation, a typical for most humans, leading to lower odds of Autism
CC in rs11246226 of DRD4, which is a typical human and leads to decreased risk of Schizophrenia.
TT in rs1800955 of DRD4, a typical associated with lower odds of intellectual disability and ADHD
CC in DRD5's rs6283. Higher odds of ADHD; mechanism of action is not exactly known
TT in rs2129785, a typical for most humans. The implications of this is that this individual does not have long form 5-HTTLPR and does not have a decrease in the risk of depression.
CC in rs6311 of HTR2A, robustly increased risk of suicidal behavior and depression. 3.6x increased risk of sexual dysfunction when taking SSRI Antidepressants
GG in rs6313 of HTR2A, lower odds for suicidal ideation.
GG in rs75459873, no risk variants for psychosis in MIR378F. Very typical genotype.
Homozygous major allele at ADCY2 gene. Associated with decreased bipolar risk.
Results Mental Health - Autism Only
TT in rs4307059, 1.42x risk of Autism, worse cell adhesion in neurons.
TT in rs10513025, typical , normal (higher) risk of autism.
TT in rs7794745, slightly increased risk for autism. Risk allele is T.
CC in rs1858830, 2x risk of autism reported by some (but not other) publications.
CC in rs1804197, common genotype. Normal (lower) risk of autism.
AA in rs2217262, typical genotype. Average (higher) risk of autism.
TT in rs1451371, More likely to smoke heavily if is a smoker.
GG in rs2060762, More likely to smoke heavily if is a smoker.
Results For Lactose Persistence
GG in MCM6's rs4988235 variation, which means this individual does not carry the European lactose persistence mutation.
CC in MCM6's rs182549, This Individual does not have any derived variants for European lactose persistence.
Results for OXTR - The Empathy Gene
GG in OXTR's rs53576 variation, which means this individual has 2 variants for higher levels of empathy at this variation.
TT in rs1042778 of OXTR, Slightly lower oxytocin & empathy? Possibly higher 'callous-unemotional' trait frequency in children
CC in OXTR's rs13316193, a associated with increased OXTR expression and higher levels of empathy.
AA in OXTR's rs7632287 variation, which means this individual has 2 variants for higher OXTR expression and increased empathy.
GG in OXTR's rs237897, two variants for higher levels of empathy in this OXTR variation. Most likely not East Asian.
Results for Diabetes
TT in rs7202877, slight decrease in risk of Type 1 Diabetes.
GG in rs12255372, decreased risk of Type 2 Diabetes.
GG in rs35011184, lower odds of Type 2 diabetes and obesity.
GG in rs2476601 variation, which leads to lower risk of various autoimmune disorders and type 1 diabetes.
GG in rs17388568, normal (lower) odds of Type 1 Diabetes.
CC in rs9273363, which leads to a 7 fold decrease in the risk of type 1 diabetes.
CC in rs7754840, which means this individual has two variants for higher odds of type 2 diabetes.
TT in rs7903146, a associated with a great increase (precisely a 2 fold increase) in the risk of type 2 diabetes.
Results for Hemochromatosis
GG in HFE's Cys282Tyr variation, which means this individual is not a carrier for the C282Y hemochromatosis mutation.
CC in HFE's His63Asp, which means this individual does not have any H63D variants and most likely doesn't have hemochromatosis.
AA in HFE's S65C variation, which means that this individual does not carry any risk variants for hemochromatosis.
Results for Alzheimers
CC in rs7412, which means no APOE2 alleles in Arg176Cys variation of the APOE gene and lower, or in other terms, normal odds of alzheimers disease.
CC in rs429358, 2 risk alleles for Alzheimers in this APOE variation, 12 to 61 times higher odds of Alzheimers than average.
TT in rs3025786, which is a typical for most humans and leads to average (slightly increased) risk of Alzheimers.
GG in PLD3's rs145999145 variation, which means this individual has a lower risk of Alzheimers.
TT in rs669, which leads to slightly decreased risk of Alzheimers.
AA in TOMM40's rs2075650, slightly decreased odds of Alzheimer's disease.
CC in rs75932628, normal (Slightly lower) risk of Alzheimer's disease
CC in rs63750847, no variants for reduced risk of Alzheimer's disease. Normal (Higher) odds of Alzheimers
Multiple sclerosis
1 risk variant in HLA-DQA1; ~2 times higher odds of MS.
no HLA-DRB1*1501 alleles, typical , normal (lower) risk for MS.
1 risk variant for MS in HLA-DRB1. Much higher (~1.5) odds of MS
AA in rs4959039, 2 (common) risk variants for MS.
Cardio-Vascular Disease Panel
AA in rs662799, normal (Lower odds of heart attack and obesity)
TT in rs602633, 2 risk variants for Coronary Heart Disease (Odds ratio = 1.11 for every T allele). Sort of uncommon.
AA in rs700651, normal (lower) risk of aneurysm
GG in rs10958409, normal (lower) risk of brain aneurysm, risk allele is A
TT in rs1333040, higher odds of brain aneurysm and heart attack.
AA in rs9298506, normal (higher) risk of aneurysm.
TT in rs6475606, increased risk for Coronary artery disease.
TT in rs10757272, 1.54x increased risk for Coronary artery disease.
CC in rs9315204, lower risk of aneurysm, common genotype.
AA in rs10757274, normal(lower) risk of heart disease.
AA in rs2383206, normal(lower) risk of heart disease.
AA in rs10757278, 0.78x reduced risk for Coronary Heart Disease. 0.77x reduced risk for Brain Aneurysm and Abdominal Aortic Aneurysm..
TT in rs1800787, likely has carotid arthery disease (6x risk).
AG in rs5082, slightly reduced risk of heart disease (G allele reduces risk).
AA in rs17576, Higher odds of heart attack, lower odds of lung cancer.
CC in rs3918242, lower (normal) odds of heart attack, risk allele is T.
Results for Myopia
AA in rs12193446, which is the typical and leads to slightly increased risk of myopia, or nearsightedness.
AA in rs7744813, which leads to a decrease in the risk of myopia.
TT in rs524952, which means an increased risk of myopia.
CC in rs4803455, two alleles for increased Myopia risk.
GG in RBFOX1's rs17648524, two alleles that protect against myopia.
CC in rs3138142, higher odds of myopia.
Miscellaneous
(Don't voice this in video!!) heterozygous in rs9332964, carries Mincropenis mutation.
(Don't voice this in video!!!) GG in SRD5A2's rs104893667 variation, which means this individual does not have micropenis.
TT in rs10784502, smaller cranium and lower IQ.
CC in rs28379706, higher IQ.
AA in rs324640, 8 points lower IQ than individuals with 'GG' .
CC in rs1815739, Better performing muscles. Likely sprinter.
AT , 1 'fat gene' variant in FTO's rs9939609. Higher odds of obesity and sleep apnea.
TT in rs10427255, likely does not have photic sneeze reflex.
GG in SCN9A rs6746030 variation, no variants for increased pain sensitivity.
TT, no MYBPC2 mental retardation variants, likely healthy.
AA genotype in EDAR's rs3827760, Likely no shovel shaped incissors and not East Asian in ancestry
AA genotype in EDAR's rs260690, European facial traits. Very uncommon genotype for East Asians. Typical for Europeans.
GG in rs671 variation, Not an Asian flusher, lower odds of Alcoholism. Normal risk of Esophageal Cancer.
AA in rs1080066, average brain volume (slightly smaller). common genotype.
Drug Responce
When treated with metoprolol
rs1801252(A;A) and rs1801253(C;C) carriers: 15 point drop in Blood Pressure rs1801252(A;G) and rs1801253(C;C) carriers: 9 point drop in Blood Pressure rs1801252(A;A) and rs1801253(C;G) carriers: 6 point drop in Blood Pressure rs1801252(A;G) and rs1801253(C;G) carriers: 1 point drop in Blood Pressure
Your genotypes are : GG in rs1801252 & CC in rs1801253
CC in rs3892097, extensive CYP2D6 metabolizer
CC in rs1467558, lower (normal) risk of liver toxicity from acetominophen/tylenol/APAP
TT in rs10156191 of AOC1, decreased DOA activity, negative responce to NSAIDs. This is an uncommon genotype.
TT in rs12476047. Lower than average odds of parkinson's symptoms when treated with antipsychotics
TT in rs5092, more likely to gain weight if taking olanzapine.
TT in rs4765623, less likely to gain weight if taking olanzapine.
CC in rs3813929, higher odds of weight gain if taking olanzapine.
GG in rs518147, significantly higher odds of weight gain if taking olanzapine.
TT in AKT1's rs2494732, lower odds of Cannabis induced psychosis.
AA in rs2241802, lower odds of methamphatamine induced psychosis.
GG in rs135745, lower susceptibility to methamphetamine induced psychosis.
Albinism & Atypical Traits Panel
AA in TYR's rs28940881 variation, which means this individual does not have any Tyrosinase-negative oculocutaneous albinism mutations.
AA in TYR's rs28940878 variation, which means this individual does not have any Tyrosinase-negative oculocutaneous albinism mutations.
TT in rs61754381, which means not a carrier for 1B Tyrosinase-negative oculocutaneous albinism.
CC in TYR's rs104894313, Not Carrier of an oculocutaneous Albinism Type 1B mutation.
CC in TYRP1's rs104894130, which means this individual lacks variants for Oculocutaneous albinism type 3, and is not albino.
CC in rs987525, which leads to decreased risk of cleft lip and palate.
CC in TYRP1's rs387907171, not a Carrier of melanesian blond hair variants.
Familiar Mediterranean Fever Panel
0 risk variants in rs104895094.
0 risk variants in rs3743930.
0 risk variants in rs11466023
0 risk variants in rs61752717
0 risk variants in rs28940579.
0 risk variants in rs28940578.
0 risk variants in rs61732874.
0 risk variants in rs104895083.
0 risk variants in rs104895097.
0 risk variants in rs104895085
0 risk variants in rs104895081
0 risk variants in rs104895157
0 risk variants in rs11466024
0 risk variants in rs11466026
0 risk variants in rs79681911
0 risk variants in rs4149584
MTHFR panel
GG in MTHFR's rs1801133, normal homocysteine levels, good . Slightly lower than average odds for a variety of illnesses from autism to coronary heart disease.
GG in MTHFR's rs1801131, Number of risks associated with impaired folate metabolism. Cancer, cleft lip, dementia, arthritis, heart disease risks.
AG in rs17367504, uncommon , slightly lower blood pressure.
Cancers Panel
0 risk variants in Q356R of BRCA1
0 risk variants in BRCA1's D693N.
0 risk variants in S1140G of BRCA1
0 risk variants in K1183R of BRCA1
0 risk variants in S1613G of BRCA1
0 risk variants in N289H of BRCA2.
0 risk variants in N372H of BRCA2
GG in rs1042522 of TP53. common genotype. Slightly shorter lifespan. Higher odds of various cancers.
0 risk variants in S707P
AA in Estrogen Receptor 1 Gene's -351A>G variation. Women have lower risk of Endometriosis but normal risk for Endometrial Cancer, and more cognitive impairment with age.
AA in rs995030, 6 times Reduced risk of testicular cancer
CC in rs3782179; 9x lower odds of testicular cancer risk for men
GG in rs4474514, reduced testicular cancer risk for men
Leukemia Panel
no NQO1*3 alleles, average odds of leukemia.
GG in rs4132601, moderately (~2.5x) increased risk for acute lymphoblastic leukemia.
GG in rs662463, common , lower odds of leukemia.
Rare diseases/traits Panel
CC in rs2200733, 0.86x decreased risk of Atrial Fibrillation
TT in rs10033464, 1.4x increased risk of Atrial Fibrillation and cardioembolic stroke.
AC in rs7743761, 4.6x increased risk of Ankylosing Spondylitis. Risk allele is A.
CT in rs6457617, significantly increased risk for RA and Systemic sclerosis, risk allele is T
GG in rs11090865, common in clinvar, no risk variants for deafness.
TT in rs6151429, healthy
AA in rs10462021, typical genotype, normal risk for DSPS.
TT in rs10156191 of AOC1, decreased DOA activity, negative responce to NSAIDs. This is an uncommon genotype.
GG in rs104894637 - not a carrier for Sanfilippo syndrome risk
CC in rs104894635, no risk variants for Sanfilippo syndrome
No von Gierke's disease. CC in Arg83Cys of glucose-6-phosphatase G6PC gene.
GG in Cys1036Phe of BLM, not a carrier of variants for Bloom syndrome.
AT, or heterozygous in rs12150220, slightly increased risk for several autoimmune diseases including Addison's disease.
CC in rs1800546, normal.
TT in rs74315405, no Gerstmann–Straussler–Scheinker syndrome.
AA in rs3764147, 0 risk variants for leprosy.
GG in rs11606250, most common , but higher risk for certain autoimmune diseases.
AA, 0 risk variants in rs2302009.
Celiac Disease Panel
average, no HLA-DRB1*0301 alleles, normal risk of celiac disease and lupus.
no HLA-DQ8 haplotype, normal (lower) risk of Celiac disease.
No risk variants in CCR3
2 risk variants in IL18R1
AA in rs13119723, lower (normal) risk for celiac disease. 0 risk variants
No risk variants in R262W
Allergies Panel
TT in rs2155219, 2 alleles for higher odds of allergies. Odds Ratio for every T allele = 1.18
GG in rs7192, lower risk of developing a peanut allergy.
TC, or heterozygous in rs9275596, 1.7x (relative to TT ) increased risk for developing a peanut allergy, risk allele is C.
Androgen Receptor Gene (AR) Panel
GG in rs6152, typical (higher) odds of baldness.
CC in rs137852591, very typical ; no Androgen insensitivity.
GG in rs9332969, normal , no Reifenstein syndrome.
GG in rs9332971, normal , no Reifenstein syndrome.
Crohn's Disease Panel
CC in NOD2's Arg702Trp. Typical (lower) risk for Crohn's disease.
GG in rs2066845, normal (lower) risk for Crohn's disease. Risk allele is C.
Canavan Syndrome Panel
AA in rs63751297, 0 risk variants.
0 risk variants in Y231X.
0 risk variants in A305E.
0 risk variants in E285A.
If you have more than 0 risk variants for Canavan syndrome, that is cause for concern. May be the result of genotyping errors depending on the chip you tested with.
HIV & AIDS Panel
HIV does not develop and transition into AIDs the same way with every organism. Some are predisposed to larger viral load and quicker compromisation of the immune system while others are more resistant.
0 protective variants in C927T (Bad), most typical genotype.
0 protective variants in rs9264942 (Bad), typical genotype.
common (Good), no risk variants in rs2395029 (TT )
AA in rs2572886, 2 risk variants for increased susceptibility to AIDs and higher HIV viral load (Bad, very uncommon).
Muscular Dystrophy Myopathies
0 risk variants in rs121913574
0 risk variants for Duchenne muscular dystrophy in rs1800278
0 risk variants in rs28937903
0 risk variants in rs28937904
0 risk variants in rs28928901
0 risk alleles in rs2296949
0 risk variants in rs28937900
0 risk variants in rs193922094
Found : 0 risk variants for adrenoleukodystrophy out of 46 Total
If you have risk variants here, it is most likely caused by miscalls in your raw data.
Since ADL is an X-linked condition, males can not be carriers. If you are male over the age of 20 and see risk variants here, it is due to miscalls. Otherwise you would be dead.
Colorblindness Panel
0 risk variants in OPN1LW out of 4
0 risk variants in OPN1MW out of 8
0 risk variants in OPN1SW out of 8
FTO Gene Panel
No risk variants for obesity in rs9930506, lower risk of obesity
No fat gene variants in rs1421085, lower odds of obesity
AA in rs9937053, much higher BMI
No fat gene variants in rs11642015, lower odds of obesity
AA in rs1121980, much higher BMI. Moderate increase (2.76x) in risk for obesity
AT , 1 'fat gene' variant in FTO's rs9939609. Higher odds of obesity and sleep apnea.
GG in rs9928094, highest odds of extreme obesity
Within PFKP Gene - also implicated in Obesity
GG in rs6602024, lower BMI
Others also implicated in Obesity
GG in rs4994, highest odds of obesity. Very uncommon genotype.
CT in rs1799883, A single copy of the Thr allele associated with a moderately increased sensitivity to saturated fats. Also contributes to increased refined carb sensitivity.
TT in rs6232, lower risk of obesity and insulin sensitivity
Syncope Panel
A syncope, commonly known as fainting, is a temporary loss of consciousness and muscle tone caused by a brief reduction in blood flow to the brain. This sudden and temporary loss of consciousness typically results from a drop in blood pressure, leading to a momentary interruption of oxygen and nutrient supply to the brain. Syncope episodes are often brief, lasting only a few seconds to a couple of minutes, and individuals usually recover spontaneously once blood flow is restored. Various factors, such as dehydration, low blood sugar, or sudden changes in body position, can contribute to the occurrence of syncope.
CC in rs12465214 of ZNF804A, increased odds of Syncope. Odds ratio of ~1.1, this is the lowest pval (most statistically significant) snp for syncope risk
GG in rs1431318, ~7% decreased odds of syncope.
Used 32768 snps in the following prediction
Syncope risk is 1.003 times the average
Bio Traits Panel
AA in rs1380703, longer (typical) sleep duration
TT in rs2497938, higher risk of male pattern baldness.
CC in rs6047844, lower risk of male pattern baldness.
AG in rs66800491, higher odds of motion sickness (This is the variation with highest impact for motion sickness)
TT in rs2148710, higher predisposition to anger
Wet earwax. Normal (smellier) body odour. Normal colostrum. Typical for non-East Asians. CC in rs17822931
AA in rs1799990, higher (typical) odds of Prion disease.
Two copies of "hunter-gatherer" CLTCL1 gene variant. Reduced ability to process carbs and sugars.
AG in rs660895, 2-3x risk of rheumatoid arthritis. Slightly increased risk of IgA nephropathy - a disease in which IgA protein builds up in and damages the filtering part of the kidney (glomerulus)
CC in rs307377, common in complete genomics - no extraordinary tasting ability
GG in rs547154, no increased protection from Age-related maculopathy, most typical genotype.
CC in rs1061147, Reduced 0.34x risk of Age Related Macular Degeneration.
AA in rs662799, normal (Lower odds of heart attack and obesity)
TT in rs2282679 of GC gene, normal levels of Vitamin D.
GG in rs12785878, higher levels of Vitamin D.
GG in rs10741657, tend to have lower vitamin D levels
TT in rs7129781, decreased odds of Vitamin D insufficiency
CC in rs6544713, slightly lower LDL cholesterol
GG in rs6756629, associated with increased LDL levels, decreased HDL cholesterol levels, and increased triglyceride levels.
CC in rs560887, slightly higher blood sugar
CC in rs27072, 2x risk of severe alcohol withdrawal. Possible increased odds of ADHD
GG in rs4481887, least likely to be able to smell asparagus metabolites in urine
TT in rs10047474, increased blood pressure
GG in rs4961 (imputed through rs4963), lower blood pressure
DVT Panel
CC in rs11121615, higher odds of varicose veins. Highest pval and beta snp for this trait
AA in rs7654093, slightly lower odds of deep vein thrombosis
GG in rs1799963, lower risk of deep vein thrombosis
GG in rs113092656, lower risk of deep vein thrombosis
Blood Group Panel
CC in rs635634, higher odds for all blood types besides A. 0.92 accuracy
CC in rs8176720, not blood type A or O. 0.77 accuracy
GG in rs7030248, Likely no Blood type B or AB. Accuracy 0.74
GG in rs493014, likely blood type B or AB. Accuracy 0.75.
GG in rs687289, Likely not Blood type AB. Accuracy 0.91
GG in rs8176746, likely not blood type AB. Accuracy 0.75.
TT in rs505922, Likely blood type O. 0.8 accuracy
TT in rs529565, Likely blood type O. 0.98 accuracy
AA in rs8176740, slightly lower odds of B and O blood types
